tobacco dust sign 👁️ Shafer's Sign: When Pigment Speaks First This slit-lamp image, captured by Manuel Ángel Alcántara Delgado, MD (Conde de Valenciana), shows a classic Shafer's — also known as — Vitreous Syneresis: An Impending Posterior

Vitreous Syneresis: An Impending Posterior Vitreous Detachment (PVD) Tobacco dust," or Shafer's sign, refers to the presence of fine brown pigmented cells (from the retinal pigment epithelium) floating in the anterior vitreous. It's an important clinical clue because, in Schaffer's Sign: Schaffer's sign alludes to the clinical finding of pigment cells in the vitreous. In the absence of prior ocular surgery, this sign is considered practically pathognomonic of a Zahra Tobacco Dust CC64 A Sign of Trouble

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